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Avera Heart Hospital

4500 West 69th Street
Sioux Falls, SD 57108

Patients and Visitors

Welcome to the Avera Heart Hospital! We strive to make your stay as comfortable as possible. We understand that care from family and friends is as important as care from our staff. That is why the hospital does not limit visiting hours. We do ask you limit the number of visitors and time in the room to allow our patients to heal. We also ask that you maintain quiet in the hospital for the comfort of other patients and guests. The following information can help you get to the Avera Heart Hospital and find the necessary services and locations after you arrive.

Browse the Patient Handbook to view your patient rights and responsibilities.


From I-229 take the Louise Avenue exit and travel south to 69th Street. Turn right on 69th Street and go west 1/2 mile. 

View the Avera Heart Hospital in our Facility Directory >>

Hotels close to the hospital

  • Prairie Heart Guest House
  • AmericInn Hotel & Suites
  • Clubhouse
  • Days Inn
  • Empire Inn
  • Fairfield Inn
  • Holiday Inn Express
  • Homewood Suites
  • Radisson
  • Super 8

Attractions close to the hospital

  • Century Movie Theatre's: The Century Movie Theatre complex is the largest in the area
  • Chuck E. Cheese: Chuck E. Cheese provides fun and pizza for all
  • Empire Bowl: Empire Bowl also offers cosmic bowling for late night fun
  • Empire and Empire East Mall: The Empire and Empire East Malls feature more than 180 of the regions best stores
  • Falls Park: Enjoy the Falls of the Big Sioux River at Falls Park
  • Great Plains Zoo
  • Sertoma Butterfly House: Experience Butterflies, Bugs and Plants at the Sertoma Butterfly House
  • Washington Pavilion: The Washington Pavilion of Arts and Science is the regions premier cultural, educational and entertainment center


Click on the graphic to view an interactive map.

Guest House

The Prairie Heart Guest House is a 32 room motel-like facility connected to both North Central Heart Institute and the Avera Heart Hospital. Built on an acre of land donated by North Central Heart physicians and located adjacent to the northeast corner of North Central Heart, the guest house is comfortable, safe and affordable.

Families often need to stay with us for an undetermined amount of time, therefore, the Prairie Heart Guest House does not take reservations. To inquire about availability, please stop at the concierge desk when you arrive at the hospital or clinic. The concierge desk is located in the front lobby of the hospital.

Rooms Include

  • two queen beds
  • wireless Internet access
  • access to laundry facilities
  • hair dryers
  • two fully handicapped accessible rooms available

About the Guest House

Prairie Heart Guest House is a dream come true! The idea for affordable family lodging adjacent to the North Central Heart Institute and the Avera Heart Hospital began in 1999. Enthusiasm for the project grew quickly because of the understanding that having family nearby enhances the healing process for patients.

A non-profit organization was formed in 2000, with the final non-profit designation received in August of 2002. In 2007 the motel expanded to add a second floor to help accommodate more families. The Board of Directors includes physicians’ spouses, Avera Sisters, leaders from North Central Heart, the Avera Heart Hospital and representatives from the community.


Help Build a Dream Your gifts help to make this dream a reality. Thank you for your generous support. Our partners, including Avera McKennan, the North Central Heart Institute and Medcath Inc., have contributed significantly to this growing project.

We still need your help to make our dream come true. Please send your tax-deductible gifts to:

Prairie Heart Guest House
4510 West Prairie Heart Place
Sioux Falls, South Dakota 57108


Welcome to the À la Heart Café. Our mission is to serve wholesome, heart-healthy food that tastes great. We offer daily breakfast, lunch and supper specials along with homemade soups, salad bar, desserts, beverages and a grab-n-go cooler. The chefs at the À la Heart Café prepare meals from scratch using wholesome, fresh ingredients.

À la Heart Café Hours

Monday - Friday
Breakfast: 7:00 a.m. - 10:00 a.m.
Lunch: 11:00 a.m. - 2:00 p.m.
Snacks: 3:00 p.m. - 5:00 p.m.
Supper: 5:00 p.m. - 6:30 p.m.

Saturday, Sunday, and Holidays
Breakfast: 8:00 a.m. - 9:30 a.m.
Lunch: 12:00 p.m. - 1:30 p.m.

On weekends and holidays, the À la Heart Café is closed for the evening meal. Patient's family member may request a room service meal that can be delivered to the patient's room or to the Prairie Heart Guest House.

The Avera Heart Hospital:
Your Best Choice

You want the best for your heart, and so do we. Cutting edge technology. A national leader in cardiovascular care. Because it's about advanced technology for better outcomes. But it's also about advanced care.

A Strong Partnership

The Avera Heart Hospital is a cooperative venture between Avera McKennan and North Central Heart.

Accredited by IAC Carotid Stenting